Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline American Airlines

The cheapest airline(s) flying from Buffalo to Key West is American Airlines.

  • American Airlines American Airlines
  • United Airlines United Airlines
  • JetBlue Airways JetBlue Airways
Cheapest Month March

Travel Period: January 2025 - December 2025

The cheapest month(s) to fly from Buffalo to Key West is March.

  • Jan 2025
  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
  • Dec 2025
Cheapest Day of the Week Wednesday

The cheapest day(s) of the week to fly from Buffalo to Key West is Wednesday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Mon, 2 Dec, 2024

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      • Availability
        • M
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      • 05:20 BUF
        12:30 EYW
        7Hrs, 10m 1 Stop (MIA)
      • BUFBuffalo Airport 05:20 - EYW 12:30 7h 10m 1 Stop (MIA) Miami
      • BUFBuffalo Airport 05:20
        MIAMiami International Airport 11:15
      • MIAMiami International Airport 08:44
        EYWKey West International Airport 12:30
      • 7h 10m (2h 31m)
      • 1 Stop MIA · Miami 2h 31m
      • American Airlines (AA 4809)Embraer Emb 175
        American Airlines (AA 4646)Embraer Emb 175
      • American Airlines (AA 4809)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 05:20 BUF
        13:21 EYW
        8Hrs, 01m 1 Stop (MIA)
      • BUFBuffalo Airport 05:20 - EYW 13:21 8h 01m 1 Stop (MIA) Miami
      • BUFBuffalo Airport 05:20
        MIAMiami International Airport 12:03
      • MIAMiami International Airport 08:44
        EYWKey West International Airport 13:21
      • 8h 01m (3h 19m)
      • 1 Stop MIA · Miami 3h 19m
      • American Airlines (AA 4809)Embraer Emb 175
        American Airlines (AA 4648)Embraer Emb 175
      • American Airlines (AA 4809)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 12:04 MIA
        06:51 DCA
        7Hrs, 50m 1 Stop (EYW)
      • MIAMiami International Airport 12:04 - DCA 06:51 7h 50m 1 Stop (EYW) Key West
      • MIAMiami International Airport 12:04
        BUFBuffalo Airport 05:23
      • EYWKey West International Airport 13:13
        DCAWashington Ronald Reagan National Airport 06:51
      • 7h 50m (2h 12m)
      • 1 Stop EYW · Key West 2h 12m
      • American Airlines (AA 4051)Embraer Emb 175
        American Airlines (AA 5163)Crj 700 Canadair Regional
      • American Airlines (AA 4051)
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        • -
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      • 05:23 BUF
        10:52 EYW
        5Hrs, 29m 1 Stop (DCA)
      • BUFBuffalo Airport 05:23 - EYW 10:52 5h 29m 1 Stop (DCA) Washington
      • BUFBuffalo Airport 05:23
        DCAWashington Ronald Reagan National Airport 07:39
      • DCAWashington Ronald Reagan National Airport 06:51
        EYWKey West International Airport 10:52
      • 5h 29m (48m)
      • 1 Stop DCA · Washington 48m
      • American Airlines (AA 5163)Crj 700 Canadair Regional
        American Airlines (AA 4597)Embraer Emb 175
      • American Airlines (AA 5163)
        • M
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        • F
        • -
        • S
      • 12:03 MIA
        06:51 DCA
        7Hrs, 49m 1 Stop (EYW)
      • MIAMiami International Airport 12:03 - DCA 06:51 7h 49m 1 Stop (EYW) Key West
      • MIAMiami International Airport 12:03
        BUFBuffalo Airport 05:23
      • EYWKey West International Airport 13:12
        DCAWashington Ronald Reagan National Airport 06:51
      • 7h 49m (2h 14m)
      • 1 Stop EYW · Key West 2h 14m
      • American Airlines (AA 4051)Embraer Emb 175
        American Airlines (AA 5163)Crj 700 Canadair Regional
      • American Airlines (AA 4051)
        • M
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        • F
        • -
        • S
      • 12:03 MIA
        07:00 DCA
        7Hrs, 49m 1 Stop (EYW)
      • MIAMiami International Airport 12:03 - DCA 07:00 7h 49m 1 Stop (EYW) Key West
      • MIAMiami International Airport 12:03
        BUFBuffalo Airport 05:32
      • EYWKey West International Airport 13:21
        DCAWashington Ronald Reagan National Airport 07:00
      • 7h 49m (2h 05m)
      • 1 Stop EYW · Key West 2h 05m
      • American Airlines (AA 4648)Embraer Emb 175
        American Airlines (AA 5163)Crj 700 Canadair Regional
      • American Airlines (AA 4648)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 12:03 MIA
        08:09 CLT
        7Hrs, 21m 1 Stop (EYW)
      • MIAMiami International Airport 12:03 - CLT 08:09 7h 21m 1 Stop (EYW) Key West
      • MIAMiami International Airport 12:03
        BUFBuffalo Airport 06:00
      • EYWKey West International Airport 13:21
        CLTCharlotte Airport 08:09
      • 7h 21m (1h 40m)
      • 1 Stop EYW · Key West 1h 40m
      • American Airlines (AA 4648)Embraer Emb 175
        American Airlines (AA 1204)Airbus
      • American Airlines (AA 4648)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 06:00 BUF
        13:26 EYW
        7Hrs, 26m 1 Stop (EWR)
      • BUFBuffalo Airport 06:00 - EYW 13:26 7h 26m 1 Stop (EWR) New York City
      • BUFBuffalo Airport 06:00
        EWRNewark Liberty International Airport 10:00
      • EWRNewark Liberty International Airport 07:32
        EYWKey West International Airport 13:26
      • 7h 26m (2h 28m)
      • 1 Stop EWR · New York City 2h 28m
      • United Airlines (UA 1598)Boeing 737 900
        United Airlines (UA 1822)Boeing 737 700
      • United Airlines (UA 1598)
        • -
        • -
        • -
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        • F
        • -
        • -
      • 06:00 BUF
        13:26 EYW
        7Hrs, 26m 1 Stop (EWR)
      • BUFBuffalo Airport 06:00 - EYW 13:26 7h 26m 1 Stop (EWR) New York City
      • BUFBuffalo Airport 06:00
        EWRNewark Liberty International Airport 10:00
      • EWRNewark Liberty International Airport 07:35
        EYWKey West International Airport 13:26
      • 7h 26m (2h 25m)
      • 1 Stop EWR · New York City 2h 25m
      • United Airlines (UA 3573)Embraer 170
        United Airlines (UA 1822)Boeing 737 700
      • United Airlines (UA 3573)
        • -
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        • -
        • -
        • -
        • -
      • 06:00 BUF
        13:28 EYW
        7Hrs, 28m 1 Stop (EWR)
      • BUFBuffalo Airport 06:00 - EYW 13:28 7h 28m 1 Stop (EWR) New York City
      • BUFBuffalo Airport 06:00
        EWRNewark Liberty International Airport 10:02
      • EWRNewark Liberty International Airport 07:32
        EYWKey West International Airport 13:28
      • 7h 28m (2h 30m)
      • 1 Stop EWR · New York City 2h 30m
      • United Airlines (UA 1598)Boeing 737 900
        United Airlines (UA 1822)Boeing 737 700
      • United Airlines (UA 1598)
        • -
        • -
        • -
        • -
        • -
        • S
        • S
      • 06:00 BUF
        13:29 EYW
        7Hrs, 29m 1 Stop (EWR)
      • BUFBuffalo Airport 06:00 - EYW 13:29 7h 29m 1 Stop (EWR) New York City
      • BUFBuffalo Airport 06:00
        EWRNewark Liberty International Airport 10:03
      • EWRNewark Liberty International Airport 07:32
        EYWKey West International Airport 13:29
      • 7h 29m (2h 31m)
      • 1 Stop EWR · New York City 2h 31m
      • United Airlines (UA 1598)Boeing 737 900
        United Airlines (UA 1822)Boeing 737 700
      • United Airlines (UA 1598)
        • -
        • T
        • -
        • -
        • -
        • -
        • -
      • 06:00 BUF
        14:14 EYW
        8Hrs, 14m 1 Stop (CLT)
      • BUFBuffalo Airport 06:00 - EYW 14:14 8h 14m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 06:00
        CLTCharlotte Airport 11:40
      • CLTCharlotte Airport 08:12
        EYWKey West International Airport 14:14
      • 8h 14m (3h 28m)
      • 1 Stop CLT · Charlotte 3h 28m
      • American Airlines (AA 1204)Airbus
        American Airlines (AA 1818)Airbus
      • American Airlines (AA 1204)
        • M
        • -
        • -
        • T
        • F
        • -
        • S
      • 06:00 BUF
        14:14 EYW
        8Hrs, 14m 1 Stop (CLT)
      • BUFBuffalo Airport 06:00 - EYW 14:14 8h 14m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 06:00
        CLTCharlotte Airport 11:40
      • CLTCharlotte Airport 08:09
        EYWKey West International Airport 14:14
      • 8h 14m (3h 31m)
      • 1 Stop CLT · Charlotte 3h 31m
      • American Airlines (AA 1204)Airbus
        American Airlines (AA 1818)Airbus
      • American Airlines (AA 1204)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 06:00 BUF
        13:49 EYW
        7Hrs, 49m 1 Stop (LGA)
      • BUFBuffalo Airport 06:00 - EYW 13:49 7h 49m 1 Stop (LGA) New York City
      • BUFBuffalo Airport 06:00
        LGANew York La Guardia Airport 10:00
      • LGANew York La Guardia Airport 07:29
        EYWKey West International Airport 13:49
      • 7h 49m (2h 31m)
      • 1 Stop LGA · New York City 2h 31m
      • American Airlines (AA 4737)Embraer Emb 175
        American Airlines (AA 4600)Embraer Emb 175
      • American Airlines (AA 4737)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 06:00 BUF
        13:56 EYW
        7Hrs, 56m 1 Stop (PHL)
      • BUFBuffalo Airport 06:00 - EYW 13:56 7h 56m 1 Stop (PHL) Philadelphia
      • BUFBuffalo Airport 06:00
        PHLPhiladelphia International Airport 10:35
      • PHLPhiladelphia International Airport 07:22
        EYWKey West International Airport 13:56
      • 7h 56m (3h 13m)
      • 1 Stop PHL · Philadelphia 3h 13m
      • American Airlines (AA 5769)Er4 Embraer Rj145 Amazon
        American Airlines (AA 1898)Airbus
      • American Airlines (AA 5769)
        • M
        • -
        • -
        • T
        • F
        • S
        • S
      • 06:00 BUF
        12:00 EYW
        6Hrs, 00m 1 Stop (CLT)
      • BUFBuffalo Airport 06:00 - EYW 12:00 6h 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 06:00
        CLTCharlotte Airport 09:30
      • CLTCharlotte Airport 08:12
        EYWKey West International Airport 12:00
      • 6h (1h 18m)
      • 1 Stop CLT · Charlotte 1h 18m
      • American Airlines (AA 1204)Airbus
        American Airlines (AA 1816)Airbus
      • American Airlines (AA 1204)
        • -
        • T
        • -
        • -
        • -
        • -
        • -
      • 06:00 BUF
        11:57 EYW
        5Hrs, 57m 1 Stop (PHL)
      • BUFBuffalo Airport 06:00 - EYW 11:57 5h 57m 1 Stop (PHL) Philadelphia
      • BUFBuffalo Airport 06:00
        PHLPhiladelphia International Airport 08:30
      • PHLPhiladelphia International Airport 07:22
        EYWKey West International Airport 11:57
      • 5h 57m (1h 08m)
      • 1 Stop PHL · Philadelphia 1h 08m
      • American Airlines (AA 5769)Er4 Embraer Rj145 Amazon
        American Airlines (AA 4604)Embraer Emb 175
      • American Airlines (AA 5769)
        • M
        • -
        • -
        • T
        • F
        • S
        • S
      • 06:00 BUF
        12:14 EYW
        6Hrs, 14m 1 Stop (CLT)
      • BUFBuffalo Airport 06:00 - EYW 12:14 6h 14m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 06:00
        CLTCharlotte Airport 09:45
      • CLTCharlotte Airport 08:09
        EYWKey West International Airport 12:14
      • 6h 14m (1h 36m)
      • 1 Stop CLT · Charlotte 1h 36m
      • American Airlines (AA 1204)Airbus
        American Airlines (AA 1816)Airbus
      • American Airlines (AA 1204)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 06:00 BUF
        12:18 EYW
        6Hrs, 18m 1 Stop (CLT)
      • BUFBuffalo Airport 06:00 - EYW 12:18 6h 18m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 06:00
        CLTCharlotte Airport 09:49
      • CLTCharlotte Airport 08:12
        EYWKey West International Airport 12:18
      • 6h 18m (1h 37m)
      • 1 Stop CLT · Charlotte 1h 37m
      • American Airlines (AA 1204)Airbus
        American Airlines (AA 1816)Airbus
      • American Airlines (AA 1204)
        • M
        • -
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        • -
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      • 06:00 BUF
        12:55 EYW
        6Hrs, 55m 1 Stop (CLT)
      • BUFBuffalo Airport 06:00 - EYW 12:55 6h 55m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 06:00
        CLTCharlotte Airport 10:40
      • CLTCharlotte Airport 08:12
        EYWKey West International Airport 12:55
      • 6h 55m (2h 28m)
      • 1 Stop CLT · Charlotte 2h 28m
      • American Airlines (AA 1204)Airbus
        American Airlines (AA 2516)Airbus
      • American Airlines (AA 1204)
        • -
        • T
        • -
        • -
        • -
        • -
        • -
      • 06:00 BUF
        13:11 EYW
        7Hrs, 11m 1 Stop (EWR)
      • BUFBuffalo Airport 06:00 - EYW 13:11 7h 11m 1 Stop (EWR) New York City
      • BUFBuffalo Airport 06:00
        EWRNewark Liberty International Airport 09:45
      • EWRNewark Liberty International Airport 07:32
        EYWKey West International Airport 13:11
      • 7h 11m (2h 13m)
      • 1 Stop EWR · New York City 2h 13m
      • United Airlines (UA 1598)Boeing 737 900
        United Airlines (UA 1822)Boeing 737 700
      • United Airlines (UA 1598)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 12:03 MIA
        08:12 CLT
        7Hrs, 12m 1 Stop (EYW)
      • MIAMiami International Airport 12:03 - CLT 08:12 7h 12m 1 Stop (EYW) Key West
      • MIAMiami International Airport 12:03
        BUFBuffalo Airport 06:00
      • EYWKey West International Airport 13:12
        CLTCharlotte Airport 08:12
      • 7h 12m (1h 37m)
      • 1 Stop EYW · Key West 1h 37m
      • American Airlines (AA 4051)Embraer Emb 175
        American Airlines (AA 1204)Airbus
      • American Airlines (AA 4051)
        • M
        • -
        • -
        • T
        • F
        • -
        • S
      • 12:04 MIA
        08:12 CLT
        7Hrs, 13m 1 Stop (EYW)
      • MIAMiami International Airport 12:04 - CLT 08:12 7h 13m 1 Stop (EYW) Key West
      • MIAMiami International Airport 12:04
        BUFBuffalo Airport 06:00
      • EYWKey West International Airport 13:13
        CLTCharlotte Airport 08:12
      • 7h 13m (1h 38m)
      • 1 Stop EYW · Key West 1h 38m
      • American Airlines (AA 4051)Embraer Emb 175
        American Airlines (AA 1204)Airbus
      • American Airlines (AA 4051)
        • -
        • T
        • -
        • -
        • -
        • -
        • -
      • 12:03 MIA
        07:29 LGA
        7Hrs, 12m 1 Stop (EYW)
      • MIAMiami International Airport 12:03 - LGA 07:29 7h 12m 1 Stop (EYW) Key West
      • MIAMiami International Airport 12:03
        BUFBuffalo Airport 06:00
      • EYWKey West International Airport 13:12
        LGANew York La Guardia Airport 07:29
      • 7h 12m (1h 17m)
      • 1 Stop EYW · Key West 1h 17m
      • American Airlines (AA 4051)Embraer Emb 175
        American Airlines (AA 4737)Embraer Emb 175
      • American Airlines (AA 4051)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 06:05 BUF
        12:14 EYW
        6Hrs, 09m 1 Stop (IAD)
      • BUFBuffalo Airport 06:05 - EYW 12:14 6h 09m 1 Stop (IAD) Washington
      • BUFBuffalo Airport 06:05
        IADWashington Dulles International Airport 09:00
      • IADWashington Dulles International Airport 07:30
        EYWKey West International Airport 12:14
      • 6h 09m (1h 30m)
      • 1 Stop IAD · Washington 1h 30m
      • United Airlines (UA 6152)Embraer 175
        United Airlines (UA 6217)Embraer 175
      • United Airlines (UA 6152)
        • M
        • T
        • -
        • T
        • F
        • S
        • S
      • 06:25 BUF
        13:53 EYW
        7Hrs, 28m 1 Stop (LGA)
      • BUFBuffalo Airport 06:25 - EYW 13:53 7h 28m 1 Stop (LGA) New York City
      • BUFBuffalo Airport 06:25
        LGANew York La Guardia Airport 10:09
      • LGANew York La Guardia Airport 07:55
        EYWKey West International Airport 13:53
      • 7h 28m (2h 14m)
      • 1 Stop LGA · New York City 2h 14m
      • American Airlines (AA 4737)Embraer Emb 175
        American Airlines (AA 4584)Embraer Emb 175
      • American Airlines (AA 4737)
        • -
        • -
        • -
        • T
        • F
        • -
        • S
      • 07:00 BUF
        15:13 EYW
        8Hrs, 13m 1 Stop (ORD)
      • BUFBuffalo Airport 07:00 - EYW 15:13 8h 13m 1 Stop (ORD) Chicago
      • BUFBuffalo Airport 07:00
        ORDChicago O'Hare International Airport 11:02
      • ORDChicago O'Hare International Airport 08:04
        EYWKey West International Airport 15:13
      • 8h 13m (2h 58m)
      • 1 Stop ORD · Chicago 2h 58m
      • United Airlines (UA 329)Airbus
        United Airlines (UA 325)Boeing 737 700
      • United Airlines (UA 329)
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 08:50 BUF
        14:14 EYW
        5Hrs, 24m 1 Stop (CLT)
      • BUFBuffalo Airport 08:50 - EYW 14:14 5h 24m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 08:50
        CLTCharlotte Airport 11:40
      • CLTCharlotte Airport 11:02
        EYWKey West International Airport 14:14
      • 5h 24m (38m)
      • 1 Stop CLT · Charlotte 38m
      • American Airlines (AA 1204)Airbus
        American Airlines (AA 1818)Airbus
      • American Airlines (AA 1204)
        • -
        • -
        • W
        • -
        • -
        • -
        • -
      • 10:28 BUF
        18:55 EYW
        8Hrs, 27m 1 Stop (FLL)
      • BUFBuffalo Airport 10:28 - EYW 18:55 8h 27m 1 Stop (FLL) Broward County
      • BUFBuffalo Airport 10:28
        FLLFort Lauderdale/Hollywood Intl Airport 17:50
      • FLLFort Lauderdale/Hollywood Intl Airport 13:40
        EYWKey West International Airport 18:55
      • 8h 27m (4h 10m)
      • 1 Stop FLL · Broward County 4h 10m
      • JetBlue Airways (B6 2465)Airbus
        Silver Airways (3M 94)Atr Turboprop
      • JetBlue Airways (B6 2465)
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 11:30 BUF
        19:01 EYW
        7Hrs, 31m 1 Stop (CLT)
      • BUFBuffalo Airport 11:30 - EYW 19:01 7h 31m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 11:30
        CLTCharlotte Airport 16:44
      • CLTCharlotte Airport 13:28
        EYWKey West International Airport 19:01
      • 7h 31m (3h 16m)
      • 1 Stop CLT · Charlotte 3h 16m
      • American Airlines (AA 1476)Airbus
        American Airlines (AA 642)Airbus
      • American Airlines (AA 1476)
        • -
        • -
        • -
        • -
        • F
        • -
        • S
      • 11:30 BUF
        17:11 EYW
        5Hrs, 41m 1 Stop (CLT)
      • BUFBuffalo Airport 11:30 - EYW 17:11 5h 41m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 11:30
        CLTCharlotte Airport 14:57
      • CLTCharlotte Airport 13:28
        EYWKey West International Airport 17:11
      • 5h 41m (1h 29m)
      • 1 Stop CLT · Charlotte 1h 29m
      • American Airlines (AA 1476)Airbus
        American Airlines (AA 1443)Airbus
      • American Airlines (AA 1476)
        • -
        • -
        • -
        • -
        • F
        • -
        • S
      • 11:30 BUF
        19:44 EYW
        8Hrs, 14m 1 Stop (CLT)
      • BUFBuffalo Airport 11:30 - EYW 19:44 8h 14m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 11:30
        CLTCharlotte Airport 17:29
      • CLTCharlotte Airport 13:28
        EYWKey West International Airport 19:44
      • 8h 14m (4h 01m)
      • 1 Stop CLT · Charlotte 4h 01m
      • American Airlines (AA 1476)Airbus
        American Airlines (AA 642)Airbus
      • American Airlines (AA 1476)
        • -
        • -
        • W
        • -
        • -
        • -
        • -
      • 18:20 MIA
        13:28 CLT
        7Hrs, 59m 1 Stop (EYW)
      • MIAMiami International Airport 18:20 - CLT 13:28 7h 59m 1 Stop (EYW) Key West
      • MIAMiami International Airport 18:20
        BUFBuffalo Airport 11:30
      • EYWKey West International Airport 19:29
        CLTCharlotte Airport 13:28
      • 7h 59m (2h 38m)
      • 1 Stop EYW · Key West 2h 38m
      • American Airlines (AA 4064)Embraer Emb 175
        American Airlines (AA 1476)Airbus
      • American Airlines (AA 4064)
        • -
        • -
        • -
        • -
        • F
        • -
        • S
      • 11:32 BUF
        19:44 EYW
        8Hrs, 12m 1 Stop (CLT)
      • BUFBuffalo Airport 11:32 - EYW 19:44 8h 12m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 11:32
        CLTCharlotte Airport 17:29
      • CLTCharlotte Airport 13:43
        EYWKey West International Airport 19:44
      • 8h 12m (3h 46m)
      • 1 Stop CLT · Charlotte 3h 46m
      • American Airlines (AA 1476)Airbus
        American Airlines (AA 642)Airbus
      • American Airlines (AA 1476)
        • -
        • T
        • -
        • -
        • -
        • -
        • -
      • 11:32 BUF
        19:01 EYW
        7Hrs, 29m 1 Stop (CLT)
      • BUFBuffalo Airport 11:32 - EYW 19:01 7h 29m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 11:32
        CLTCharlotte Airport 16:44
      • CLTCharlotte Airport 13:43
        EYWKey West International Airport 19:01
      • 7h 29m (3h 01m)
      • 1 Stop CLT · Charlotte 3h 01m
      • American Airlines (AA 1476)Airbus
        American Airlines (AA 642)Airbus
      • American Airlines (AA 1476)
        • M
        • -
        • -
        • T
        • -
        • -
        • -
      • 11:32 BUF
        17:11 EYW
        5Hrs, 39m 1 Stop (CLT)
      • BUFBuffalo Airport 11:32 - EYW 17:11 5h 39m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 11:32
        CLTCharlotte Airport 14:57
      • CLTCharlotte Airport 13:43
        EYWKey West International Airport 17:11
      • 5h 39m (1h 14m)
      • 1 Stop CLT · Charlotte 1h 14m
      • American Airlines (AA 1476)Airbus
        American Airlines (AA 1443)Airbus
      • American Airlines (AA 1476)
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      • 18:20 MIA
        13:43 CLT
        7Hrs, 57m 1 Stop (EYW)
      • MIAMiami International Airport 18:20 - CLT 13:43 7h 57m 1 Stop (EYW) Key West
      • MIAMiami International Airport 18:20
        BUFBuffalo Airport 11:32
      • EYWKey West International Airport 19:29
        CLTCharlotte Airport 13:43
      • 7h 57m (2h 23m)
      • 1 Stop EYW · Key West 2h 23m
      • American Airlines (AA 4064)Embraer Emb 175
        American Airlines (AA 1476)Airbus
      • American Airlines (AA 4064)
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      • 11:35 BUF
        17:11 EYW
        5Hrs, 36m 1 Stop (CLT)
      • BUFBuffalo Airport 11:35 - EYW 17:11 5h 36m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 11:35
        CLTCharlotte Airport 14:57
      • CLTCharlotte Airport 13:33
        EYWKey West International Airport 17:11
      • 5h 36m (1h 24m)
      • 1 Stop CLT · Charlotte 1h 24m
      • American Airlines (AA 1476)Airbus
        American Airlines (AA 1443)Airbus
      • American Airlines (AA 1476)
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      • 11:35 BUF
        18:56 EYW
        7Hrs, 21m 1 Stop (CLT)
      • BUFBuffalo Airport 11:35 - EYW 18:56 7h 21m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 11:35
        CLTCharlotte Airport 16:39
      • CLTCharlotte Airport 13:33
        EYWKey West International Airport 18:56
      • 7h 21m (3h 06m)
      • 1 Stop CLT · Charlotte 3h 06m
      • American Airlines (AA 1476)Airbus
        American Airlines (AA 642)Airbus
      • American Airlines (AA 1476)
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      • 18:20 MIA
        13:33 CLT
        7Hrs, 54m 1 Stop (EYW)
      • MIAMiami International Airport 18:20 - CLT 13:33 7h 54m 1 Stop (EYW) Key West
      • MIAMiami International Airport 18:20
        BUFBuffalo Airport 11:35
      • EYWKey West International Airport 19:29
        CLTCharlotte Airport 13:33
      • 7h 54m (2h 33m)
      • 1 Stop EYW · Key West 2h 33m
      • American Airlines (AA 4064)Embraer Emb 175
        American Airlines (AA 1476)Airbus
      • American Airlines (AA 4064)
        • -
        • -
        • -
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        • S
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      How far is Key West from Buffalo?

      The flight distance between Buffalo and Key West is 2056km. Check all available flights on Wego.

      When is the earliest and latest flight of the day?

      The earliest flight of the day departs at 05:20. The last flight of the day departs at 05:20. See the full list of flight times on Wego.

      All Airports in Buffalo

      Buffalo Airport BUF

      All Airports in Key West

      Key West International Airport EYW

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